Vitals Elke Dag
Elke Dag Tablets has been the most popular variant within the Elke Dag series for years. This is a one-a-day multi in tablet form, suitable for adults from 18 years of age. It is a carefully designed multi with essential micronutrients and special additions. In the formulation, well-absorbable substances and compound forms have been chosen as much as possible, in the correct proportions and with the most optimal dosages. Choices have naturally been made here, as only a limited amount fits into a tablet. Elke Dag will pass the comparison with other multis with flying colours and is the first choice of many therapists for good reason.

What is new?
The composition has been revised, based on the most recent scientific insights, tailored to current data regarding nutritional status in the Netherlands and the optimal intake amounts per nutrient. For some nutrients, the dosage has been reduced. This applies, for example, to the various B vitamins. In a multi suitable for long-term use as a supplement to the diet, it is in many cases not necessary to dose these too highly. And for some nutrients, the substantiation of the necessity as daily basic supplementation was lacking, which is why they have been omitted from the formula. This concerns inositol, PABA, and chromium. By lowering the B vitamins, omitting the three mentioned nutrients, and using different compound forms here and there, space was created in the tablet and space in the price to increase the dosage of other important nutrients. For example, more is known about the desired intakes of choline, and this has been increased from 25 mg to 85 mg per tablet. In addition, the dosage of vitamin C has been increased from 100 mg to 160 mg, the dosage of magnesium is three times higher with an increase from 30 mg to 100 mg, and the dosage of calcium has gone from 30 mg to 150 mg, making it five times higher! These are nutrients that take up a relatively large amount of space, but of which it is truly important to get enough daily. Furthermore, the formula has been made more complete with meso-zeaxanthin as a supplement to the lutein and zeaxanthin. And finally, vitamin K1 has been added and the amounts of vitamin K2, D3, and Q10 have been increased.

For whom
Elke Dag is specifically designed for adults. Vitals has developed separate multis for children, the elderly, and for women who are pregnant or wish to become so. See also Elke Dag Junior, Elke Dag 50+, and Elke Dag Mama. Young people and (young) adults can choose Elke Dag Basis (1 per day) or Elke Dag Capsules (young people 1 capsule per day and adults 2 capsules per day). In addition, there is Elke Dag Powder for those who prefer not to swallow a capsule or tablet, or prefer to mix the multi into something. Adults and the elderly who want the best of the best choose Elke Dag Platinum (two tablets per day).

B vitamins in optimal forms and dosages
The Elke Dag multis contain generous but responsible amounts of B vitamins. Careful consideration has been given to daily needs and what the average intakes and their lower limits are. This also takes into account the extent to which the body is able to convert the various B vitamins, the latest scientific insights, and the safe upper limits.

All formulas also contain the biologically active forms of vitamin B2 (riboflavin-5’-phosphate), B6 (pyridoxal-5’-phosphate), B12 (methyl- and adenosylcobalamine), and folic acid (5-methyltetrahydrofolate glucosamine salt). These are the forms as used by the body, and research shows that these have a higher bioavailability in the body.

Vitamin B6 as pyridoxal-5’-phosphate
Very high dosages of vitamin B6 can, in incidental cases, lead to tingling or numbness in hands or feet. That is why in the Netherlands, a maximum safe upper limit of 21 mg per day for adults is used for vitamin preparations. The Elke Dag multis remain far below that (maximum 4.2 mg). In addition, only pyridoxal-5’-phosphate (P-5’-P) is used, the biologically active form of vitamin B6, and not pyridoxine-HCL which still has to be converted in the body. Further research is currently being conducted into whether the aforementioned incidental side effects only occur with vitamin B6 in the form of pyridoxine-HCL and not, or to a lesser extent, with pyridoxal-5’-phosphate. There are indications that only pyridoxine-HCL in high dosages is toxic to nerve cells.

Folic acid as 5-methyltetrahydrofolate
Folic acid (pteroylmonoglutamic acid), which is usually used in food supplements for the sake of stability, is a synthetic form that does not occur as such in nature. In food, it occurs as folate. Folic acid from supplements must be converted by the body into tetrahydrofolate and then into 5-methyltetrahydrofolate (5-MTHF). Research shows that this complex conversion process is far from optimal in a significant group of people. Supplementation with 5-MTHF bypasses this problem.

The Elke Dag multis use the superior form 5-methyltetrahydrofolate, bound to glucosamine salt (with the brand name Quatrefolic®). This binding with glucosamine salt (from a plant source) makes it possible to keep the biologically active form stable and ensures optimal absorbability. Studies show that Quatrefolic® has a higher water solubility, stability, and bioavailability. In addition, 5-MTHF is able to cross the blood-brain barrier, unlike the 'regular' (synthetic) form of folic acid.

Vitamin B12 as methyl- and adenosylcobalamin
The absorption of vitamin B12 from food is a complex process. In addition, there are indications that the RI (formerly RDA) of 2.5 mcg per day has been underestimated and the needs of healthy adults and the elderly can vary and reach over 20 mcg per day. Due to the safety of vitamin B12 supplementation and the sometimes difficult absorption of B12 from food and supplements, the Elke Dag multis contain generous dosages in the biologically active forms methyl- and adenosylcobalamin.

Many other B12 products and multis contain cyanocobalamin, which is a cheaper, synthetic form of vitamin B12 that does not occur as such in nature and must be converted by the body into the active forms. In this process, the cyanide part is decoupled from the cobalamine (B12) and must then be cleared by the body. Studies show that vitamin B12 in the form of methyl- and adenosylcobalamin has a higher bioavailability than cyanocobalamin.

Generous vitamin D dosages, from a plant source
European government agencies have determined in recent years that the level for an adequate intake of vitamin D from food should be higher (15 mcg) and that the maximum permitted dosage could be increased (100 mcg). In the Netherlands, they are still cautious and indicate that 10 mcg is sufficient and that the maximum amount is 75 mcg. Strangely enough, the RI (or RDA) has remained stuck at 5 mcg. But in the orthomolecular world, the importance of higher dosages has been known for some time. Leading vitamin D experts advise that the vitamin D level (calcidiol level) of adults should be at least 75 nmol/l. To maintain such a vitamin D level, an oral dose of vitamin D3 of an estimated 25-75 mcg per day is required.

The Elke Dag multis contain generous dosages of vitamin D3 (cholecalciferol). This form is much more effective than vitamin D2 (ergocalciferol) in increasing the vitamin D level. Moreover, the new Elke Dag multis use plant-based vitamin D3 (Vitamin D3V®). It is produced from algae, and not from sheep's wool fat (like the vast majority of vitamin D3 products). This means all multis in the Elke Dag series are now also suitable for vegans.

Vitamin K1 and K2
The Elke Dag multis now also contain a small amount of vitamin K1, in addition to a higher dosage of vitamin K2. Vitamin K1 is mainly absorbed by the liver and primarily ensures the activation of clotting factors, while vitamin K2 has a greater bioavailability, is distributed much more across body tissues, and is partly for that reason more effective in activating other vitamin K-dependent enzymes such as osteocalcin and MGP. These ensure, among other things, that calcium is properly absorbed and ends up in the right place, namely in the bones.

The body will always use vitamin K first for the vital blood clotting function. Because vitamin K2 is a much more expensive raw material than vitamin K1, a small amount of K1 is added to the multis so that it can be used for the priority blood clotting function and the K2 can be used for the other, very important functions.

The regularly established RI for vitamin K is, incidentally, based on the amount needed for normal blood clotting. Strangely enough, the optimal dosage of vitamin K regarding other vitamin K-dependent body processes was not considered here.

Stability of vitamin K2
Vitamin K2 appears to be a very sensitive substance. Particularly in combination with calcium and/or magnesium, the content of this vitamin in a tablet or capsule decreases rapidly. Using vitamin K2 in a product with high dosages of calcium and/or magnesium is technically a real challenge. Vitals therefore uses a K2 ingredient with the brand name K2Vital® Delta, which is even stable in a formula with many of these minerals. A patented micro-encapsulation process is used, in which the fat-soluble K2 particles are protected with two layers against air, light, and interaction with other ingredients. Vitals had research conducted in an independent laboratory into the stability of K2Vital® Delta, and it came out best in the test. It was compared with other brands of vitamin K2, specifically in combination with the ingredients used in Vitals products. The conclusions were that protecting the K2 is absolutely necessary, that the K2 content remained well stable with K2Vital® Delta, and that it was superior to the other K2 ingredients.

Natural calcium and magnesium from the sea
From now on, calcium and magnesium from the brand Aquamin®, originating from the sea, will be used for the multis. In the tablets, much higher dosages are achieved with this than with previously used compound forms, while the absorption of these ingredients is proven to be good.

The magnesium (Aquamin Magnesium) is obtained from the seawater of the Irish Sea, and studies show that it is well absorbed in the body. In addition to approximately 35% elemental magnesium, the raw material also contains small amounts of more than 70 trace elements.

The calcium (Aquamin Calcium) comes from a red alga called Lithothamnium calcareum. This species of algae absorbs minerals and trace elements from the sea and stores them. When alive, it has a beautiful red/pink colour, but when it dies, it calcifies and turns white or light grey. Only calcified red alga is harvested, from the waters along the coast of Iceland. In addition to 32% calcium, the raw material also contains 3% magnesium and small amounts of more than 70 trace elements.

The synergetic effect of the natural trace element profile of this calcium and magnesium is possibly part of the explanation for the better absorbability and the impressive studies conducted with it.

Iron, zinc, copper, and manganese as amino acid chelate (bisglycinate)
For the minerals iron, zinc, copper, and manganese, amino acid chelates (bisglycinates) have been chosen. In this form, each mineral particle is strongly bound (chelated) to two molecules of the amino acid glycine. Minerals in this compound form reach the small intestine well and are very well absorbed. They are also gentle on the stomach, which can be a major advantage, particularly in the case of iron. Furthermore, Vitals specifically chooses the amino acid chelates from Albion Minerals, recognisable by the trademark TRAACS®, which stands for The Real Amino Acid Chelate System. This brand was created to make a clear distinction from other, potentially inferior, unstable amino acid chelates. Albion has registered more than 100 patents worldwide that guarantee the process, science, and structure of their amino acid chelated minerals.

Unique: relatively high dosage of choline
Choline has been included in multis as a sort of standard for a long time. But almost always in low dosages (between 10-30 mg). Because not much was known about it. But more and more is now known! In 2012, three health claims for choline were approved by the European Commission, which apply at a dosage of at least 82.5 mg. It is important for normal lipid metabolism, homocysteine metabolism, and normal liver function. In 2016, an RDA was established in America for the first time at 550 mg/day, based on clinical research specifically intended to determine daily requirements. In 2016, EFSA also judged that choline is an essential nutrient but has not yet established an RI. The adequate intake was set at 400 mg/day, based on average intake in European countries, and not based on the American study that arrived at 550 mg/day. The average intake of adults in Europe fluctuates between 291 and 468 mg/day. Reason enough to include a generous amount of choline in a daily multi!

In the Elke Dag multis, choline from the brand VitaCholine® is used. This brand stands for superior quality and much research has been done with it.

Lutein, zeaxanthin, and meso-zeaxanthin
Lutein, zeaxanthin, and meso-zeaxanthin are natural carotenoids. In the body, a high concentration of these substances is found in the retina and macula lutea ('yellow spot'). The body cannot produce lutein and zeaxanthin itself but must obtain them from the diet. These are found in green leafy vegetables, and red, yellow, and orange types of fruit and vegetables, among others. Meso-zeaxanthin occurs only very limitedly in food (shrimp, salmon skin, trout skin and flesh). It is mainly produced in the retina by conversion of lutein through an enzymatic reaction. It can, however, be well supplemented. It has been known for a relatively short time that meso-zeaxanthin is a very good addition and is preferred over supplementation of only lutein and zeaxanthin.

Suitable for vegetarians and vegans.

• vitamins B1, B2, B3, B5, B6, B12, biotin, vitamin C, calcium, magnesium, iron, iodine, copper, and manganese support energy levels
• vitamins B2, B3, B5, B6, B12, folate, vitamin C, magnesium, and iron can help with fatigue
• vitamins A, B6, B12, folate, vitamins C, D, iron, copper, selenium, and zinc have a positive influence on the immune system
• vitamins B2, C, E, copper, manganese, selenium, and zinc protect cells from oxidative damage
• vitamins B1, B2, B3, B6, B12, biotin, vitamin C, calcium, magnesium, iodine, and copper support the nervous system
• iron, iodine, and zinc contribute to normal cognitive function
• vitamins B1, B3, B6, B12, biotin, folate, vitamin C, and magnesium support mental functions (such as concentration and memory) and mood
• vitamin B5 and folate contribute to resistance against stress
• vitamins A, B2, and zinc are good for eyesight
• vitamins C, D, K, calcium, manganese, and zinc are good for the bones
• vitamin K contributes to the absorption of calcium in the bones
• vitamin K is necessary for the normal course of blood clotting
• vitamins C, D, and calcium are good for the condition of the teeth
• biotin, selenium, and zinc are good for the condition of the hair
• copper contributes to normal pigmentation of the skin and hair
• vitamins A, B2, B3, C, biotin, iodine, and zinc are good for the condition of the skin
• selenium and zinc are good for the condition of the nails
• iodine and selenium support normal thyroid function
• vitamin D, calcium, and magnesium support muscle function
• vitamin B1 contributes to the normal functioning of the heart
• calcium and magnesium play a role in the production of cells and tissues
• calcium supports the maintenance of healthy digestion
• magnesium helps in building proteins in the body
• magnesium contributes to a good electrolyte balance
• choline contributes to normal homocysteine metabolism
• choline contributes to the maintenance of the structure of cell membranes and normal lipid metabolism

Composition

Composition per daily dose of 1 tablet:		RI*
Beta-carotene (from Dunaliella salina) (is converted to vitamin A	1.8 mg 300 µg-RE	- 37.5%)
Vitamin A (retinyl acetate)	300 µg-RE	37.5%
Vitamin B1 (thiamine-HCl)	4.4 mg	400%
Vitamin B2 (sodium riboflavin-5’-phosphate)	4.2 mg	300%
Vitamin B3 (niacinamide)	24 mg	150%
Vitamin B5 (calcium-d-pantothenate)	18 mg	300%
Vitamin B6 (pyridoxal-5’-phosphate)	3.5 mg	250%
Folate (5-MTHF glucosamine salt, Quatrefolic®)	200 µg	100%
Vitamin B12 (50% methylcobalamin, 50% adenosylcobalamin)	20 µg	800%
Biotin	75 µg	150%
Choline (bitartrate, VitaCholine®)	85 mg	-
Vitamin C (magnesium ascorbate)	160 mg	200%
Vitamin D3 (vegan, Vitamin D3V®)	25 µg	500%
Vitamin E (natural, d-alpha-tocopheryl hydrogen succinate)	36 mg-TE	300%
Mixed tocopherols (beta, gamma, delta)	10 mg	-
Vitamin K1 (phytomenadione)	37.5 µg	50%
Vitamin K2 (menaquinone-7, K2Vital® Delta)	75 µg	100%
Calcium (carbonate e.g. from red alga, Aquamin® Calcium)	150 mg	19%
Iron (bisglycinate, Ferrochel®, TRAACS®)	7 mg	50%
Iodine (potassium iodide)	75 µg	50%
Copper (bisglycinate, TRAACS®)	0.25 mg	25%
Magnesium (hydroxide from seawater, Aquamin® Magnesium, magnesium ascorbate)	100 mg	27%
Manganese (bisglycinate, TRAACS®)	1 mg	50%
Molybdenum (sodium molybdate)	25 µg	50%
Selenium (L-selenomethionine)	58 µg	105%
Zinc (bisglycinate, TRAACS®)	5 mg	50%
Citrus bioflavonoid complex	20 mg	-
Lutein (from Tagetes erecta)	5 mg	-
Zeaxanthin (from Tagetes erecta)	1 mg	-
Meso-zeaxanthin (from Tagetes erecta)	5 mg	-
Q10 (natural, ubiquinone)	40 mg	-
* RI = Reference Intake
Quatrefolic® is a patented product and a registered trademark of Gnosis. VitaCholine® is a registered trademark of Balchem Corporation. Vitamin D3V® is a registered trademark of ProTecNutra Ltd. K2Vital® Delta is a registered trademark of Kappa Bioscience. Aquamin® is a registered trademark of Marigot Ltd. Ferrochel® and TRAACS® (The Real Amino Acid Chelate System) are registered trademarks of Albion Minerals.

 

Ingredients
Minerals (calcium, magnesium, iron, zinc, selenium, molybdenum, manganese, copper, iodine), bulking agent (microcrystalline cellulose [cellulose gel]), vitamins (C, E, B3, B5, D3, K2, B2, B1, B6, A, K1, folate, biotin, B12), choline bitartrate, Q10, anti-caking agents (silicon dioxide, magnesium salts of fatty acids), citrus bioflavonoid complex, mixed tocopherols, lutein, meso-zeaxanthin, glazing agents (hydroxypropyl methylcellulose, glycerol, hydroxypropyl cellulose), Dunaliella salina, zeaxanthin.

Use
Take 1 tablet per day with a meal and water. Adhere to the recommended dosage.

This food supplement is not suitable for children up to and including 10 years of age (legally required statement for products with more than 20 µg of vitamin D per daily dose).

The vitamin K in this product makes it unsuitable for use alongside coumarin derivatives (anticoagulants such as acenocoumarol and phenprocoumon). These medicines are also called vitamin K antagonists and their effectiveness is reduced by the intake of vitamin K from food and supplements.

Storage instructions
Store in a dry, closed place at room temperature.

Manufacturer / Distributor
Vitals Voedingssupplementen, Pieter Lieftinckweg 29, 1505 HX Zaandam

This product is a food supplement.

Do not exceed recommended dosage.

A varied, balanced diet and a healthy lifestyle are important. A food supplement is not a substitute for a varied diet.

Keep out of reach of young children.

Store in a dry, closed place at room temperature, unless otherwise advised on the label.

Consult an expert before using supplements in case of pregnancy, lactation, medication use, and illness.